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毕业论文代写:依托泊苷介绍分析

依托泊苷是一种从足跖草中提取的化合物。这种植物很难种植。因此,他们发现可以将产酶基因从己膜转移到苯那米那。这是一种很容易种植的类似烟草的植物。工程植物被发现只生产纳克的依托泊苷苷配基,作为依托泊苷的前体。

毕业论文代写:依托泊苷介绍分析

依托泊苷是抗癌化疗药物。本品为植物生物碱,具有拓扑异构酶II抑制剂的作用。目前,它被用作足叶草毒素的半合成衍生物,被发现具有抗肿瘤活性。依托泊苷抑制DNA被发现,并被发现与拓扑异构酶II和DNA形成复合物。该复合物用于诱导双链DNA的断裂,并被发现阻止拓扑异构酶II结合的修复。积累的DNA会将DNA分解到细胞分裂的有丝分裂阶段。这最终会导致细胞凋亡。然后进入细胞周期的G2和S期。目前正在研究纳米颗粒形式给药的可行性。依托泊苷的全部潜力尚未得到充分利用。

毕业论文代写:依托泊苷介绍分析

Etoposide is a compound that is extracted from the Podophyllum hexandrum. It is difficult to grow this plant. Owing to this, it was found that they can transfer the enzyme producing gene from P. hexandrum to Nicotiano benthamiana. This is a tobacco-like plant that is easier to grow. Engineered plant is found to produce only nanograms of etoposide aglycone as a precursor to Etoposide The prolific growth of the yeast cell can lead to better production。

毕业论文代写:依托泊苷介绍分析

Etoposide is anti-cancer chemotherapy drug. This drug is a plant alkaloid and it functions as a topoisomerase II inhibitor. In the current times, it is used as a semisynthetic derivative of podophyllotoxin that is found to exhibit antitumor activity. The Etoposide inhibit DNA is found and is found to form a complex with the topoisomerase II and DNA. The complex is used to induce the break in the double stranded DNA and is found to prevent repair of the topoisomerase II binding. The accumulated then breaks the DNA into the mitotic phase of cell division. This eventually causes apoptosis. This then enters into the G2 and S phases of cell cycle. Currently, the feasibility of administering the medicine in the form of Nano particles is being studied. The complete potential of the Etoposide is yet to be harnessed completely.