毕业论文代写-纳米药物对脑癌的影响

| 29-10月-2019 | 澳洲论文代写

本篇毕业论文代写-纳米药物对脑癌的影响讲了随着癌症的进展,人们发现血脑屏障的组织间液压力也在快速增加。由于这个问题,在大脑中发现的大部分药物被大量移除。我们发现,在脑血脑屏障中,脑组织间液的压力要高得多。这使得药物的渗透性更加困难。因此,在脑癌期间,BBB变得更加难以处理。即使纳米颗粒能够穿过血脑屏障,药物在大脑中的储存和分配也会受到阻碍。有必要寻找新的方法来解决BBB中组织流体压力的问题。本篇毕业论文代写文章由澳洲第一论文 Assignment First辅导网整理,供大家参考阅读。

Hence any nanomedicine that is developed needs to fundamentally handle the astrocyte foot process and the pericytes of the BBB. This has been an impediment while delivering the drug to the brain. These inherent issues need to be addressed while developing nano medicine.

Interstital fluid pressure is the pressure that is found in the BBB inherently to maintain the fluid balance [9]. This pressure balance is based on the dynamic conditions existing in the brain. There are several factors that ensure that there is smooth balance. Starling equation can be applied to understand how interstitial fluid pressure varies in the brain according to the organic conditions impacting the brain. Starling equation has numerous benefits [9]. Starling equation states that fluid movement in the capillary is dependent on the balance of oncotic pressure gradient and hydrostatic pressure gradient [11]. In the case of malignant cancer it is found that there is an uncontrolled activity of the brain [9]. As the cancer progresses it has been found that the interstitial fluid pressure of the BBB is also found to increase at a rapid pace [11]. Owing to this issue there is considerable removal of the bulk of the drugs that is found in the brain. The interstitial fluid pressure in the brain is found to be substantially higher in the BBB. This makes permeability of the drugs even harder. Hence BBB becomes even more difficult to tackle during the times of brain cancer. Retention and distribution of the medicines in the brain are also hindered even if the nanoparticles manage to cross across the BBB [10]. There is a need for novel approaches to address this issue of interstitial fluid pressure in the BBB.

Apart from this even if the nanomedicines manage to cross across the BBB and show effective retention and distribution there is issue of cytotoxicity. This cytotoxicity is found to vary across the different nanoparticles. This has been investigated in detail in the following analysis.

相关的论文代写的话题

英文论文代写essay的写作方法

英文论文代写essay的写作方法

英文论文代写essay的写作方法 在澳洲留学过程中,essay的写作可以说是再熟悉不过了,它是学生作业中很常见的一种,可是对于不少留学生来说却是一个噩梦,让人十分烦恼。今天,老师就为大家详细讲解一下英文论文代写essay的写作方法,希望可以帮助到大家。

澳洲essay代写如何才能写好呢?

澳洲essay代写如何才能写好呢?

澳洲essay代写如何才能写好呢?Critical Essay是Essay写作中的一种,它指的是对于观点或者文章的评论。评论文不只是批判,而应该是客观的评论,尽量减少主观因素带来的影响。那么,澳洲essay代写如何才能写好呢?下面我们就一起来了解一下吧。

澳洲代寫essay如何能保質保量完成呢?

澳洲代寫essay如何能保質保量完成呢?

澳洲代寫essay如何能保質保量完成呢?我們常常會聽到留學生有這樣的抱怨,自己花費了很長的時間和精力去完成essay,可是最後分數卻不高,而這種現象是常見的,因爲不是每一個人的essay寫作水平都很高。那麼,澳洲代寫essay如何能保質保量完成呢?下面就讓澳洲第一論文 Assignment First輔導網老師來爲大家詳細講解一下。